Our Central Reading Centres (CRCs) play several crucial roles in the conduct of clinical trials, providing key input during the study design, preparation of the operations manual, as well as site and photographer certification. They provide an objective and standardised grading of images from study participants to confirm study eligibility, and to evaluate disease responses at subsequent study visits.

CRCs need to strictly adhere to Good Clinical Practice (GCP) guidelines, as well as established standard operating procedures in order to ensure that images are properly graded. The role of CRCs will continue to evolve, and include the use of web-based image transmission and grading platforms.